• Discusses key advances in biomedical research and their impact on clinical studies
• Reviews each topic in depth, providing background and perspective on current literature
• Puts new developments in a broader context, permitting comparison of different ideas and careful evaluation of their importance
• Includes contributions from expert opinion leaders at recognized centers of excellence

This title reviews current knowledge of the mechanisms contributing to heart failure. Editor Richard Walsh and an internationally renowned team of contributors discuss key advances in molecular and cell biology, biochemistry, and pharmacology, focusing on advances that have a direct bearing on current clinical studies. It highlights developments across a broad range of disciplines, with in-depth coverage of each topic providing background and perspective on current literature. By setting new advances in a broader context, this text allows readers to compare different ideas and evaluate their importance in their own areas of research or clinical practice.